Dopaminergic Control of Striatal Cholinergic Interneurons Underlies Cocaine-Induced Psychostimulation

Dopaminergic Control of Striatal Cholinergic Interneurons Underlies Cocaine-Induced Psychostimulation

Summary: Cocaine drastically elevates dopamine (DA) levels in the striatum, a brain region that is critical to the psychomotor and rewarding properties of the drug. DA signaling regulates intrastriatal circuits connecting medium spiny neurons (MSNs) with afferent fibers and interneurons. While the c...

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Bibliographic Details
Main Authors: Robert G. Lewis, Marcello Serra, Daniela Radl, Michela Gori, Catherine Tran, Sharon E. Michalak, Christopher D. Vanderwal, Emiliana Borrelli
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720304277

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http://www.sciencedirect.com/science/article/pii/S2211124720304277

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