Pharmacokinetics and brain distribution of the therapeutic peptide liraglutide by a novel LC–MS/MS analysis

Pharmacokinetics and brain distribution of the therapeutic peptide liraglutide by a novel LC–MS/MS analysis

Abstract Liraglutide is a glucagon-like peptide-1 (GLP-1) analog that has been utilized for the treatment of type 2 diabetes mellitus. Liraglutide at a higher dose also shows beneficial effects in weight loss, which prompted its widespread use as an anti-obesity drug. The potential of liraglutide to...

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Bibliographic Details
Main Authors: Hyeon Seok Oh, Minkyu Choi, Tae Suk Lee, Yejin An, Eun Ji Park, Tae Hwan Kim, Soyoung Shin, Beom Soo Shin
Format: Article
Language:English
Published: SpringerOpen 2023-03-01
Series:Journal of Analytical Science and Technology
Subjects:
Glucagon-like peptide-1
Liraglutide
LC–MS/MS
Pharmacokinetics
Bioavailability
Brain distribution
Online Access:https://doi.org/10.1186/s40543-023-00382-5

Internet

https://doi.org/10.1186/s40543-023-00382-5

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