Characterisation of Dermanyssus gallinae glutathione S-transferases and their potential as acaricide detoxification proteins

Abstract Background Glutathione S-transferases (GSTs) facilitate detoxification of drugs by catalysing the conjugation of the reduced glutathione (GSH) to electrophilic xenobiotic substrates and therefore have a function in multi-drug resistance. As a result, knowledge of GSTs can inform both drug r...

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Bibliographic Details
Main Authors: Kathryn Bartley, Harry W. Wright, Robert S. Bull, John F. Huntley, Alasdair J. Nisbet
Format: Article
Language:English
Published: BMC 2015-06-01
Series:Parasites & Vectors
Subjects:
Online Access:https://doi.org/10.1186/s13071-015-0960-9