Involvement of Mrgprd-expressing nociceptors-recruited spinal mechanisms in nerve injury-induced mechanical allodynia

Summary: Mechanical allodynia and hyperalgesia are intractable symptoms lacking effective clinical treatments in patients with neuropathic pain. However, whether and how mechanically responsive non-peptidergic nociceptors are involved remains elusive. Here, we showed that von Frey-evoked static allo...

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Bibliographic Details
Main Authors: Liangbiao Wang, Xiaojing Su, Jinjin Yan, Qiaofeng Wu, Xiang Xu, Xinyue Wang, Xiaoqing Liu, Xiaoyuan Song, Zhi Zhang, Wei Hu, Xinfeng Liu, Yan Zhang
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223008416