Impact of Immunoglobulin M-Type Donor-Specific Human Leukocyte Antigen–Antibody Levels in Supernatants from Cultured Peripheral Blood Mononuclear Cells as Predictors of Antibody-Mediated Rejection

Impact of Immunoglobulin M-Type Donor-Specific Human Leukocyte Antigen–Antibody Levels in Supernatants from Cultured Peripheral Blood Mononuclear Cells as Predictors of Antibody-Mediated Rejection

Background: Antibody-mediated rejection (AMR) is a crucial barrier in the long-term prognosis of transplant recipients. Methods: Peripheral blood mononuclear cells (PBMCs) were collected from kidney allograft recipients (<i>N</i> = 41) and cultured in vitro for 1 week. Furthermore, the s...

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Bibliographic Details
Main Authors: Ryoichi Imamura, Yoshiko Matsuda, Koichi Tsutahara, Norio Nonomura, Shiro Takahara
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Pathogens
Subjects:
antibody-mediated rejection
kidney transplantation
donor-specific anti-HLA antibody
IgM antibody
IgM memory B cell
in vitro culture assay
Online Access:https://www.mdpi.com/2076-0817/9/9/733

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https://www.mdpi.com/2076-0817/9/9/733

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