Cardiovascular effects associated with chimeric antigen receptor T cell therapy in cancer patients: A meta-analysis

Cardiovascular effects associated with chimeric antigen receptor T cell therapy in cancer patients: A meta-analysis

BackgroundAlthough numerous studies confirmed the marked efficacy of chimeric antigen receptor T cells (CAR-T cells) in many hematologic malignancies, severe cardiovascular toxicities remain to be a major obstacle when incorporating this technology. Furthermore, previous individual investigations re...

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Bibliographic Details
Main Authors: Li-Rong Chen, Ya-Jia Li, Zheng Zhang, Ping Wang, Tao Zhou, Kai Qian, Yu-Xin Fan, Yu Guo, Gong-Hao He, Lei Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Oncology
Subjects:
chimeric antigen receptor T cell
CAR-T cell therapy
cardiovascular toxicities
safety
hematologic malignancies
cancer patients
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.924208/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.924208/full

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