MACROTROMBOCITOPENIA RELACIONADA À MUTAÇÃO GENE MYH9

MACROTROMBOCITOPENIA RELACIONADA À MUTAÇÃO GENE MYH9

Introdução: Entre as trombocitopenias congênitas, há um grupo de doenças causadas por um defeito no gene MYH9, localizado no cromossomo 22q12-13 que codifica a cadeia pesada da miosina não muscular IIA. Em plaquetas ela é a principal isoforma dessa proteína que, em combinação com actina gera força m...

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Bibliographic Details
Main Authors:	AA Araujo, SM Luporini, FM Barbosa, ICO Hegg, M Pizza, ML Borsato, LMG Coelho, P Bruniera
Format:	Article
Language:	English
Published:	Elsevier 2023-10-01
Series:	Hematology, Transfusion and Cell Therapy
Online Access:	http://www.sciencedirect.com/science/article/pii/S2531137923012737

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