Peripheral thickening of the sarcomeres and pointed end elongation of the thin filaments are both promoted by SALS and its formin interaction partners.

During striated muscle development the first periodically repeated units appear in the premyofibrils, consisting of immature sarcomeres that must undergo a substantial growth both in length and width, to reach their final size. Here we report that, beyond its well established role in sarcomere elong...

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Bibliographic Details
Main Authors: Dávid Farkas, Szilárd Szikora, A S Jijumon, Tamás F Polgár, Roland Patai, Mónika Ágnes Tóth, Beáta Bugyi, Tamás Gajdos, Péter Bíró, Tibor Novák, Miklós Erdélyi, József Mihály
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1011117&type=printable