Complement-dependent bystander injury to neurons in AQP4-IgG seropositive neuromyelitis optica
Abstract Background Aquaporin-4-immunoglobulin G (AQP4-IgG) seropositive neuromyelitis optica spectrum disorder (herein called NMO) is an autoimmune disease of the central nervous system in which AQP4-IgG binding to AQP4 on astrocytes results in complement-dependent astrocyte injury and secondary in...
| Główni autorzy: | , , |
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| Format: | Artykuł |
| Język: | English |
| Wydane: |
BMC
2018-10-01
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| Seria: | Journal of Neuroinflammation |
| Hasła przedmiotowe: | |
| Dostęp online: | http://link.springer.com/article/10.1186/s12974-018-1333-z |