Modulation of experimental acute lung injury by exosomal miR-7704 from mesenchymal stromal cells acts through M2 macrophage polarization

Modulation of experimental acute lung injury by exosomal miR-7704 from mesenchymal stromal cells acts through M2 macrophage polarization

Acute lung injury (ALI) is a life-threatening condition with limited treatment options. The pathogenesis of ALI involves macrophage-mediated disruption and subsequent repair of the alveolar barriers, which ultimately results in lung damage and regeneration, highlighting the pivotal role of macrophag...

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Bibliographic Details
Main Authors: Wei-Ting Lin, Hao-Hsiang Wu, Chien-Wei Lee, Yu-Fan Chen, Lawrence Huang, Jennifer Hui-Chun Ho, Oscar Kuang-Sheng Lee
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MT: non-coding RNAs
IFN /TNF-stimulated MSCs
mesenchymal stromal cell
exosome
miR-7704
macrophage polarization
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253123003207

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http://www.sciencedirect.com/science/article/pii/S2162253123003207

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