Protection against dengue virus infection in mice by administration of antibodies against modified nonstructural protein 1.

Protection against dengue virus infection in mice by administration of antibodies against modified nonstructural protein 1.

BACKGROUND: Infection with dengue virus (DENV) may cause life-threatening disease with thrombocytopenia and vascular leakage which are related to dysfunction of platelets and endothelial cells. We previously showed that antibodies (Abs) against DENV nonstructural protein 1 (NS1) cross-react with hum...

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Main Authors: Shu-Wen Wan, Yi-Tien Lu, Chia-Hui Huang, Chiou-Feng Lin, Robert Anderson, Hsiao-Sheng Liu, Trai-Ming Yeh, Yu-Ting Yen, Betty A Wu-Hsieh, Yee-Shin Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3962419?pdf=render

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http://europepmc.org/articles/PMC3962419?pdf=render

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