Unraveling the mechanisms and evolution of a two-domain module in IQGAP proteins for controlling eukaryotic cytokinesis

Summary: The IQGAP family of proteins plays a crucial role in cytokinesis across diverse organisms, but the underlying mechanisms are not fully understood. In this study, we demonstrate that IQGAPs in budding yeast, fission yeast, and human cells use a two-domain module to regulate their localizatio...

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Bibliographic Details
Main Authors: Kangji Wang, Hiroki Okada, Carsten Wloka, Erfei Bi
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472301522X