8OHdG as a marker for Huntington disease progression

8OHdG as a marker for Huntington disease progression

Leukocyte 8-hydroxydeoxyguanosine (8OHdG) is an indicator of oxidative stress, impaired metabolism, and mitochondrial dysfunction, features that have been implicated in Huntington disease (HD). Increased levels of 8OHdG have been reported in the caudate, parietal cortex, and peripherally in the seru...

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Bibliographic Details
Main Authors: Jeffrey D. Long, Wayne R. Matson, Andrew R. Juhl, Blair R. Leavitt, Jane S. Paulsen
Format: Article
Language:English
Published: Elsevier 2012-06-01
Series:Neurobiology of Disease
Subjects:
8OHdG
Huntington disease
Biomarker
Oxidative stress
Mitochondrial dysfunction
PREDICT-HD
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996112000678

Internet

http://www.sciencedirect.com/science/article/pii/S0969996112000678

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