mRNA-to-protein translation in hypoxia

mRNA-to-protein translation in hypoxia

Abstract Cells respond to hypoxia by shifting cellular processes from general housekeeping functions to activating specialized hypoxia-response pathways. Oxygen plays an important role in generating ATP to maintain a productive rate of protein synthesis in normoxia. In hypoxia, the rate of the canon...

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Bibliographic Details
Main Authors: Nancy T. Chee, Ines Lohse, Shaun P. Brothers
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Molecular Cancer
Subjects:
Hypoxia
mRNA-to-protein translation
HIF
Hypoxia-inducible factor
Cancer
HIF inhibitors
Online Access:http://link.springer.com/article/10.1186/s12943-019-0968-4

Internet

http://link.springer.com/article/10.1186/s12943-019-0968-4

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