Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits

Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits

Zobrazit další vydání (1)

Abstract Background Age-related macular degeneration (AMD) is a common condition of vision loss with disease development strongly influenced by environmental and genetic factors. Recently, 34 loci were associated with AMD at genome-wide significance. So far, little is known about a genetic overlap b...

Podrobná bibliografie
Hlavní autoři:	Felix Grassmann, Christina Kiel, Martina E. Zimmermann, Mathias Gorski, Veronika Grassmann, Klaus Stark, International AMD Genomics Consortium (IAMDGC), Iris M. Heid, Bernhard H. F. Weber
Médium:	Článek
Jazyk:	English
Vydáno:	BMC 2017-03-01
Edice:	Genome Medicine
Témata:	Age-related macular degeneration AMD Genetic risk scores GRS Genetic association studies Complex traits
On-line přístup:	http://link.springer.com/article/10.1186/s13073-017-0418-0

Podobné jednotky

Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits
Autor: Grassmann, F, a další
Vydáno: (2017)

Pleiotropic Locus 15q24.1 Reveals a Gender-Specific Association with Neovascular but Not Atrophic Age-Related Macular Degeneration (AMD)
Autor: Christina Kiel, a další
Vydáno: (2020-10-01)

Vitronectin and Its Interaction with PAI-1 Suggests a Functional Link to Vascular Changes in AMD Pathobiology
Autor: Fabiola Biasella, a další
Vydáno: (2022-05-01)

Potential Therapeutic Candidates for Age-Related Macular Degeneration (AMD)
Autor: Sonali Nashine
Vydáno: (2021-09-01)

Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease
Autor: Thomas W. Winkler, a další
Vydáno: (2020-08-01)

Biomarkers for the Progression of Intermediate Age-Related Macular Degeneration
Autor: Eleonora M. Lad, a další
Vydáno: (2023-09-01)

Prevalence of insomnia and depression in patients with age-related macular degeneration
Autor: Elżbieta Nowak, a další
Vydáno: (2018-07-01)

Etiopathogenesis of non-exudative age-related macular degeneration (literature review)
Autor: M. M. Bikbov, a další
Vydáno: (2022-03-01)

Genetic Risk Assessment of Degenerative Eye Disease (GRADE): study protocol of a prospective assessment of polygenic risk scores to predict diagnosis of glaucoma and age-related macular degeneration
Autor: Georgina L Hollitt, a další
Vydáno: (2023-10-01)

Off-Label Use of Bevacizumab in Patients Diagnosed with Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis
Autor: João Estarreja, a další
Vydáno: (2024-07-01)

Intravitreal Brolucizumab in Patients with Aflibercept-Resistant Neovascular Age-Related Macular Degeneration
Autor: Ashwin Gupta, a další
Vydáno: (2022-01-01)

Antioxidants in Age-Related Macular Degeneration: Lights and Shadows
Autor: Uday Pratap Singh Parmar, a další
Vydáno: (2025-01-01)

Berries and Their Active Compounds in Prevention of Age-Related Macular Degeneration
Autor: Xiang Li, a další
Vydáno: (2024-12-01)

Patterns of Gene Expression, Splicing, and Allele-Specific Expression Vary among Macular Tissues and Clinical Stages of Age-Related Macular Degeneration
Autor: Treefa Shwani, a další
Vydáno: (2023-11-01)

Genetic Association between MMP9 and Choroidal Neovascularization in Age-Related Macular Degeneration
Autor: Elliott H. Sohn, MD, a další
Vydáno: (2021-03-01)

Efficacy and Safety of Nutraceutical Support in Age-Related Macular Degeneration Patients
Autor: S. V. Yanchenko, a další
Vydáno: (2023-01-01)

Eye Drop with Fas-Blocking Peptide Attenuates Age-Related Macular Degeneration
Autor: Yujong Yi, a další
Vydáno: (2024-03-01)

Current and Novel Therapeutic Approaches for Treatment of Neovascular Age-Related Macular Degeneration
Autor: Reem H. ElSheikh, a další
Vydáno: (2022-11-01)

Dry and neovascular “wet” age-related macular degeneration: Upcoming therapies
Autor: Audrey Yan, a další
Vydáno: (2025-01-01)

Linking Adiponectin and Its Receptors to Age-Related Macular Degeneration (AMD)
Autor: Mayank Choubey, a další
Vydáno: (2023-11-01)

Dietary and Lifestyle Factors Modulate the Activity of the Endogenous Antioxidant System in Patients with Age-Related Macular Degeneration: Correlations with Disease Severity
Autor: Zofia Ulańczyk, a další
Vydáno: (2020-10-01)

A comprehensive review on early detection of drusen patterns in age-related macular degeneration using deep learning models
Autor: Kiruthika M, a další
Vydáno: (2025-02-01)

Treatment Methods Dry Form of Age Macular Degeneration — History and Prospects. Review
Autor: A. N. Kulikov, a další
Vydáno: (2023-10-01)

Early and intermediate age-related macular degeneration: update and clinical review
Autor: García-Layana A, a další
Vydáno: (2017-10-01)

Choriocapillaris in Age-Related Macular Degeneration
Autor: Giovanni Neri, a další
Vydáno: (2024-08-01)

Clinical validation of a genetic model to estimate the risk of developing choroidal neovascular age-related macular degeneration
Autor: Hageman Gregory S, a další
Vydáno: (2011-07-01)

Prevalence of age-related macular degeneration in Iran and its projections through 2050: a systematic review and meta-analysis
Autor: Amirhossein Roshanshad, a další
Vydáno: (2023-11-01)

The role of the carotenoids, lutein and zeaxanthin, in protecting against age-related macular degeneration: A review based on controversial evidence
Autor: Sacu Stefan, a další
Vydáno: (2003-12-01)

Age-Related Macular Degeneration: Therapeutic Strategies and Future Approaches
Autor: Răzvan Vasile ROPCIUC
Vydáno: (2024-05-01)

Incremental economic burden associated with exudative age-related macular degeneration: a population-based study
Autor: Siin Kim, a další
Vydáno: (2019-11-01)

Deep Learning Approach for Age-related Macular Degeneration Detection Using Retinal Images: Efficacy Evaluation of Different Deep Learning Models
Autor: Ngoc Thien Le, a další
Vydáno: (2023-12-01)

Age-related macular degeneration: suitability of optogenetic therapy for geographic atrophy
Autor: Grace A. Borchert, a další
Vydáno: (2024-07-01)

Plasma Metabolites Associated with OCT Features of Age-Related Macular Degeneration
Autor: Ines Lains, MD, PhD, a další
Vydáno: (2024-01-01)

Genetic risk factors and age-related macular degeneration (AMD)
Autor: Maryam Mousavi, a další
Vydáno: (2013-10-01)

Role of Complement in the Onset of Age-Related Macular Degeneration
Autor: Niloofar Piri, a další
Vydáno: (2023-05-01)

Innate immune biology in age-related macular degeneration
Autor: Karina Ascunce, a další
Vydáno: (2023-02-01)

Pipeline therapies for neovascular age related macular degeneration
Autor: Sruthi Arepalli, a další
Vydáno: (2021-10-01)

Global Insights from Patients, Providers, and Staff on Challenges and Solutions in Managing Neovascular Age-Related Macular Degeneration
Autor: Anat Loewenstein, a další
Vydáno: (2024-12-01)

Case Series on Initial Responses to Intravitreal Brolucizumab in Patients with Recalcitrant Chronic Wet Age-Related Macular Degeneration
Autor: Avaylon J, a další
Vydáno: (2020-05-01)

Metabolomic-derived endotypes of age-related macular degeneration (AMD): a step towards identification of disease subgroups
Autor: Kevin Mendez, a další
Vydáno: (2024-05-01)