GGDEF domain as spatial on-switch for a phosphodiesterase by interaction with landmark protein HubP

Abstract In bacteria, the monopolar localization of enzymes and protein complexes can result in a bimodal distribution of enzyme activity between the dividing cells and heterogeneity of cellular behaviors. In Shewanella putrefaciens, the multidomain hybrid diguanylate cyclase/phosphodiesterase PdeB,...

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Bibliographic Details
Main Authors: Tim Rick, Vanessa Kreiling, Alexander Höing, Svenja Fiedler, Timo Glatter, Wieland Steinchen, Georg Hochberg, Heike Bähre, Roland Seifert, Gert Bange, Shirley K. Knauer, Peter L. Graumann, Kai M. Thormann
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-022-00297-w