Aptamer-siRNA Chimeras: Discovery, Progress, and Future Prospects

Synthetic nucleic acid ligands (aptamers) have emerged as effective delivery tools for many therapeutic oligonucleotide-based drugs, including small interfering RNAs (siRNAs). In this review, we summarize recent progress in the aptamer selection technology that has made possible the identification o...

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Bibliographic Details
Main Authors: Sven Kruspe, Paloma H. Giangrande
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/5/3/45