Personalized cancer vaccines from bacteria-derived outer membrane vesicles with antibody-mediated persistent uptake by dendritic cells

Personalized cancer vaccines from bacteria-derived outer membrane vesicles with antibody-mediated persistent uptake by dendritic cells

Nanocarriers with intrinsic immune adjuvant properties can activate the innate immune system while delivering tumor antigen, thus efficiently facilitating antitumor adaptive immunity. Bacteria-derived outer membrane vesicles (OMVs) are an excellent candidate due to their abundance of pathogen associ...

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Bibliographic Details
Main Authors: Jie Liang, Keman Cheng, Yao Li, Jiaqi Xu, Yiwei Chen, Nana Ma, Qingqing Feng, Fei Zhu, Xiaotu Ma, Tianjiao Zhang, Yale Yue, Guangna Liu, Xinjing Guo, Zhiqiang Chen, Xinwei Wang, Ruifang Zhao, Ying Zhao, Jian Shi, Xiao Zhao, Guangjun Nie
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2022-01-01
Series:Fundamental Research
Subjects:
Tumor vaccine
Outer membrane vesicles
Antibody modification
Antigen display
Dendritic cell uptake
Myeloid derived suppressor cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2667325821003058

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http://www.sciencedirect.com/science/article/pii/S2667325821003058

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