Generation of three clones (JUCGRMi002-A, B, C) of induced pluripotent stem cells from a Parkinson’s disease patient with SNCA duplication
Parkinson’s disease is the second most common neurodegenerative disorder and is pathologically characterized by synuclein-rich aggregations (Lewy bodies) in neurons. Multiplication of the synuclein gene (SNCA) increases the mRNA and protein levels of synuclein, resulting in autosomal dominant heredi...
| Prif Awduron: | , , , , , |
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| Fformat: | Erthygl |
| Iaith: | English |
| Cyhoeddwyd: |
Elsevier
2024-02-01
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| Cyfres: | Stem Cell Research |
| Mynediad Ar-lein: | http://www.sciencedirect.com/science/article/pii/S1873506123002829 |