ProNGF processing in adult rat tissues and bioactivity of NGF prodomain peptides

ProNGF processing in adult rat tissues and bioactivity of NGF prodomain peptides

The neurotrophin nerve growth factor (NGF) and its precursor proNGF are both bioactive and exert similar or opposite actions depending on the cell target and its milieu. The balance between NGF and proNGF is crucial for cell and tissue homeostasis and it is considered an indicator of pathological co...

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Bibliographic Details
Main Authors: Marie Anne Makoudjou, Elena Fico, Pamela Rosso, Viviana Triaca, Lucio De Simone, Daniela Rossetti, Franca Cattani, Marcello Allegretti, Paola Tirassa
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:FEBS Open Bio
Subjects:
apoptosis
inflammation
nerve growth factor
peptides
prodomain
proNGF
Online Access:https://doi.org/10.1002/2211-5463.13768

Internet

https://doi.org/10.1002/2211-5463.13768

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