Combination of genomic instability score and TP53 status for prognosis prediction in lung adenocarcinoma
Abstract The genomic instability (GI) /homologous recombination deficiency (HRD) score, calculated as the sum of the events of loss of heterozygosity (LOH), large-scale state transition (LST) and telomere allele imbalance (TAI), is used to guide the choice of treatment in several cancers, but its re...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-10-01
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Series: | npj Precision Oncology |
Online Access: | https://doi.org/10.1038/s41698-023-00465-x |