Combination of genomic instability score and TP53 status for prognosis prediction in lung adenocarcinoma

Combination of genomic instability score and TP53 status for prognosis prediction in lung adenocarcinoma

Abstract The genomic instability (GI) /homologous recombination deficiency (HRD) score, calculated as the sum of the events of loss of heterozygosity (LOH), large-scale state transition (LST) and telomere allele imbalance (TAI), is used to guide the choice of treatment in several cancers, but its re...

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Bibliographic Details
Main Authors: Juan Feng, Yang Lan, Feng Liu, Ye Yuan, Jia Ge, Sen Wei, Hu Luo, Jianjun Li, Tao Luo, Xiuwu Bian
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-023-00465-x

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