Neuroprotective Effect of Solid Lipid Nanoparticles Loaded with <i>Lepidium sativum</i> (L.) Seed Bioactive Components Enhance Bioavailability and Wnt/β-Catenin/Camk-II Signaling Cascade in SH-SY5Y Neuroblastoma Cells

Neuroprotective Effect of Solid Lipid Nanoparticles Loaded with <i>Lepidium sativum</i> (L.) Seed Bioactive Components Enhance Bioavailability and Wnt/β-Catenin/Camk-II Signaling Cascade in SH-SY5Y Neuroblastoma Cells

The primary pathological hallmark of Alzheimer’s disease (AD) is the formation and accumulation of neurofibrillary tangles and plaques, which result from the aggregation of amyloid-<i>β</i> (A<i>β</i>) induced by oxidative stress. The effectiveness of Alzheimer’s disease (AD)...

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Bibliographic Details
Main Authors: Nada Al-Saran, Pandurangan Subash-Babu, Laila Naif Al-Harbi, Bahauddeen M. Alrfaei, Ali A. Alshatwi
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Nanomaterials
Subjects:
SLNP
A<i>β</i> (1-42) fibrils
oxidative stress
A<i>β</i>-neurotoxicity
Wnt/Camk-II
post synapse
Online Access:https://www.mdpi.com/2079-4991/14/2/199

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https://www.mdpi.com/2079-4991/14/2/199

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