Glutamic Acid Decarboxylase 1 Gene Methylation and Panic Disorder Severity: Making the Connection by Brain Gray Matter Volume

Glutamic Acid Decarboxylase 1 Gene Methylation and Panic Disorder Severity: Making the Connection by Brain Gray Matter Volume

ObjectiveThis study aimed to test the hypothesis that the relationship between glutamic acid decarboxylase (GAD) 1 gene methylation and severity of clinical symptoms of panic disorder (PD) is mediated by the effect of GAD1 gene methylation on gray matter volume (GMV) and the effect of GMV on PD.Meth...

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Bibliographic Details
Main Authors: Huiqin Wu, Yuan Zhong, Huazhen Xu, Huachen Ding, Shiting Yuan, Yun Wu, Gang Liu, Na Liu, Chun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Psychiatry
Subjects:
panic disorder
glutamic acid decarboxylase 1
gray matter volumes
DNA methylation
mediation effect
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2022.853613/full

Internet

https://www.frontiersin.org/articles/10.3389/fpsyt.2022.853613/full

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