Cellular and molecular biology of sirtuins in cardiovascular disease

Cellular and molecular biology of sirtuins in cardiovascular disease

Sirtuins (SIRTs) are a nicotinic adenine dinucleotide (+) -dependent histone deacetylase that regulates critical signaling pathways in prokaryotes and eukaryotes. Studies have identified seven mammalian homologs of the yeast SIRT silencing message regulator 2, namely, SIRT1-SIRT7. Recent in vivo and...

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Bibliographic Details
Main Authors: Yong-Ping Liu, Ri Wen, Chun-Feng Liu, Tie-Ning Zhang, Ni Yang
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Sirtuin
Drug discovery
Myocardial hypertrophy
Heart failure
Ischemic reperfusion
Atherosclerosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223007217

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http://www.sciencedirect.com/science/article/pii/S0753332223007217

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