CtBP: A mediator of a metabolic switch from homeostasis to carcinogenesis
The dimeric form of C-terminus binding protein (CtBP), which is responsible for a balanced transcription rate of genes involved in the homeostatic processes, is a global corepressor. CtBP dimerization and formation of the CtBP corepressor complex require NADH. Under a normal NADH/NAD+ ratio, CtBP is...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2025-03-01
|
Series: | Endocrine and Metabolic Science |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666396124000529 |