Ursolic Acid Reverses the Chemoresistance of Breast Cancer Cells to Paclitaxel by Targeting MiRNA-149-5p/MyD88

Ursolic Acid Reverses the Chemoresistance of Breast Cancer Cells to Paclitaxel by Targeting MiRNA-149-5p/MyD88

Paclitaxel (PTX) is widely used as a front-line chemotherapy for breast cancer treatment. However, its clinical applications are limited by the development of chemoresistance. The objective of this study was to investigate the reversal effects of ursolic acid (UA) on PTX resistance and the possible...

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Bibliographic Details
Main Authors: Fenfen Xiang, Yan Fan, Zhenhua Ni, Qiaoli Liu, Zhaowei Zhu, Zixi Chen, Wenbin Hao, Honghong Yue, Rong Wu, Xiangdong Kang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Oncology
Subjects:
ursolic acid
paclitaxel
breast cancer
resistance
miR-149-5p
MyD88
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00501/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00501/full

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