Dietary nitrate supplementation prevents radiotherapy-induced xerostomia

Management of salivary gland hypofunction caused by irradiation (IR) therapy for head and neck cancer remains lack of effective treatments. Salivary glands, especially the parotid gland, actively uptake dietary nitrate and secrete it into saliva. Here, we investigated the effect of dietary nitrate o...

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Bibliographic Details
Main Authors: Xiaoyu Feng, Zhifang Wu, Junji Xu, Yipu Xu, Bin Zhao, Baoxing Pang, Xingmin Qu, Liang Hu, Lei Hu, Zhipeng Fan, Luyuan Jin, Dengsheng Xia, Shimin Chang, Jingsong Wang, Chunmei Zhang, Songlin Wang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/70710