Polyphenol Supplementation Did Not Affect Insulin Sensitivity and Fat Deposition During One-Month Overfeeding in Randomized Placebo-Controlled Trials in Men and in Women

Polyphenol Supplementation Did Not Affect Insulin Sensitivity and Fat Deposition During One-Month Overfeeding in Randomized Placebo-Controlled Trials in Men and in Women

Two randomized placebo-controlled double-blind paralleled trials (42 men in Lyon, 19 women in Lausanne) were designed to test 2 g/day of a grape polyphenol extract during 31 days of high calorie-high fructose overfeeding. Hyperinsulinemic-euglycemic clamps and test meals with [1,1,1-13C3]-triolein w...

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Bibliographic Details
Main Authors: Bérénice Segrestin, Pauline Delage, Angéline Nemeth, Kevin Seyssel, Emmanuel Disse, Julie-Anne Nazare, Stéphanie Lambert-Porcheron, Laure Meiller, Valerie Sauvinet, Stéphanie Chanon, Chantal Simon, Hélène Ratiney, Olivier Beuf, François Pralong, Naba-al-Huda Yassin, Alexia Boizot, Mélanie Gachet, Kathryn J. Burton-Pimentel, Hubert Vidal, Emmanuelle Meugnier, Nathalie Vionnet, Martine Laville
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Nutrition
Subjects:
polyphenols
overfeeding
insulin sensitivity
nutritional intervention
insulin resistance
grape polyphenols
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.854255/full

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https://www.frontiersin.org/articles/10.3389/fnut.2022.854255/full

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