Predicting scale-dependent chromatin polymer properties from systematic coarse-graining
Abstract Simulating chromatin is crucial for predicting genome organization and dynamics. Although coarse-grained bead-spring polymer models are commonly used to describe chromatin, the relevant bead dimensions, elastic properties, and the nature of inter-bead potentials are unknown. Using nucleosom...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-07-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-39907-2 |