A fast machine-learning-guided primer design pipeline for selective whole genome amplification.

Addressing many of the major outstanding questions in the fields of microbial evolution and pathogenesis will require analyses of populations of microbial genomes. Although population genomic studies provide the analytical resolution to investigate evolutionary and mechanistic processes at fine spat...

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Bibliographic Details
Main Authors: Jane A Dwivedi-Yu, Zachary J Oppler, Matthew W Mitchell, Yun S Song, Dustin Brisson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-04-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010137