NRBF2 regulates the chemoresistance of small cell lung cancer by interacting with the P62 protein in the autophagy process

NRBF2 regulates the chemoresistance of small cell lung cancer by interacting with the P62 protein in the autophagy process

Summary: Reversing chemotherapy resistance in small cell lung cancer (SCLC) is crucial to improve patient prognosis. The present study aims to investigate the underlying mechanisms in SCLC chemoresistance. We see that nuclear receptor binding factor 2 (NRBF2) is a poor prognostic factor in SCLC. The...

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Bibliographic Details
Main Authors: Weitao Shen, Peng Luo, Yueqin Sun, Wei Zhang, Ningning Zhou, Hongrui Zhan, Qingxi Zhang, Jie Shen, Anqi Lin, Quan Cheng, Qiongyao Wang, Jian Zhang, Hai-Hong Wang, Ting Wei
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:iScience
Subjects:
Cell biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222007428

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http://www.sciencedirect.com/science/article/pii/S2589004222007428

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