Association between organic cation transporter genetic polymorphisms and metformin response and intolerance in T2DM individuals: a systematic review and meta-analysis

Association between organic cation transporter genetic polymorphisms and metformin response and intolerance in T2DM individuals: a systematic review and meta-analysis

BackgroundVariants in organic cation transporter (OCT) genes play a crucial role in metformin pharmacokinetics and are critical for diabetes treatment. However, studies investigating the effect of OCT genetic polymorphisms on metformin response have reported inconsistent results. This review and met...

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Bibliographic Details
Main Authors: Aiyu Peng, Chunmei Gong, Yuanfei Xu, Xiongshun Liang, Xiaoping Chen, Wenxu Hong, Junxia Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Public Health
Subjects:
organic cation transporters
genetic polymorphisms
type 2 diabetes mellitus
metformin response
metformin intolerance
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2023.1183879/full

Internet

https://www.frontiersin.org/articles/10.3389/fpubh.2023.1183879/full

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