Phenotypic Displays of Cholinergic Enzymes Associate With Markers of Inflammation, Neurofibrillary Tangles, and Neurodegeneration in Pre- and Early Symptomatic Dementia Subjects

Phenotypic Displays of Cholinergic Enzymes Associate With Markers of Inflammation, Neurofibrillary Tangles, and Neurodegeneration in Pre- and Early Symptomatic Dementia Subjects

BackgroundCholinergic drugs are the most commonly used drugs for the treatment of Alzheimer’s disease (AD). Therefore, a better understanding of the cholinergic system and its relation to both AD-related biomarkers and cognitive functions is of high importance.ObjectivesTo evaluate the relationships...

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Bibliographic Details
Main Authors: Unnur D. Teitsdottir, Taher Darreh-Shori, Sigrun H. Lund, Maria K. Jonsdottir, Jon Snaedal, Petur H. Petersen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
cerebrospinal fluid
acetylcholinesterase
butyrylcholinesterase
cholinergic system
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.876019/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2022.876019/full

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