In vivo and in vitro safety evaluation of fermented Citrus sunki peel extract: acute and 90-day repeated oral toxicity studies with genotoxicity assessment

In vivo and in vitro safety evaluation of fermented Citrus sunki peel extract: acute and 90-day repeated oral toxicity studies with genotoxicity assessment

Abstract Background Citrus sunki Hort. ex Tanaka peel has been traditionally used as an ingredient in folk medicine due to its therapeutic effects on promotion of splenic health and diuresis as well as relief of gastrointestinal symptoms. Although a growing interest in health-promoting natural produ...

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Bibliographic Details
Main Authors: Jin-Sung Park, Eun-Young Cho, Yun-Soon Kim, Euna Kwon, Kang-Min Han, Seung-Yup Ku, Chul-Woo Jung, Jun-Won Yun, Jeong-Hwan Che, Byeong-Cheol Kang
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Citrus sunki
Fermented peel extract
Acute toxicity
Subchronic toxicity
Mutagenicity
Clastogenicity
Online Access:http://link.springer.com/article/10.1186/s12906-020-03079-z

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http://link.springer.com/article/10.1186/s12906-020-03079-z

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