The Druggable Pocketome of Corynebacterium diphtheriae: A New Approach for in silico Putative Druggable Targets

The Druggable Pocketome of Corynebacterium diphtheriae: A New Approach for in silico Putative Druggable Targets

Diphtheria is an acute and highly infectious disease, previously regarded as endemic in nature but vaccine-preventable, is caused by Corynebacterium diphtheriae (Cd). In this work, we used an in silico approach along the 13 complete genome sequences of C. diphtheriae followed by a computational asse...

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Bibliographic Details
Main Authors: Syed S. Hassan, Syed B. Jamal, Leandro G. Radusky, Sandeep Tiwari, Asad Ullah, Javed Ali, Behramand, Paulo V. S. D. de Carvalho, Rida Shams, Sabir Khan, Henrique C. P. Figueiredo, Debmalya Barh, Preetam Ghosh, Artur Silva, Jan Baumbach, Richard Röttger, Adrián G. Turjanski, Vasco A. C. Azevedo
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Genetics
Subjects:
Corynebacterium diphtheria
pocketome
druggable genome
structural proteomics
putative therapeutic targets
highly druggable (HD)
Online Access:http://journal.frontiersin.org/article/10.3389/fgene.2018.00044/full

Internet

http://journal.frontiersin.org/article/10.3389/fgene.2018.00044/full

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