Pien-Tze-Huang prevents hepatocellular carcinoma by inducing ferroptosis via inhibiting SLC7A11-GSH-GPX4 axis

Pien-Tze-Huang prevents hepatocellular carcinoma by inducing ferroptosis via inhibiting SLC7A11-GSH-GPX4 axis

Abstract Background Malignant transformation from hepatic fibrosis to carcinogenesis may be a therapeutic target for hepatocellular carcinoma (HCC). The aim of this study was to evaluate anti-cancer efficacy of Pien-Tze-Huang (PZH), and to investigate the underlying mechanisms by integrating transcr...

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Bibliographic Details
Main Authors:	Xiangying Yan, Yudong Liu, Congchong Li, Xia Mao, Tengteng Xu, Zhixing Hu, Chu Zhang, Na Lin, Ya Lin, Yanqiong Zhang
Format:	Article
Language:	English
Published:	BMC 2023-06-01
Series:	Cancer Cell International
Subjects:	Hepatocellular carcinoma Pien-Tze-Huang Ferroptosis Solute carrier family 7 member 11 Glutathione Glutathione peroxidase 4
Online Access:	https://doi.org/10.1186/s12935-023-02946-2

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