Thyroid carcinoma‐featured telomerase activation and telomere maintenance: Biology and translational/clinical significance

Abstract Background Telomerase is a ribonucleoprotein complex consisting of a catalytic component telomerase reverse transcriptase (TERT), internal RNA template and other co‐factors, and its essential function is to synthesize telomeric DNA, repetitive TTAGGG sequences at the termini of linear chrom...

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Bibliographic Details
Main Authors: Xiaotian Yuan, Huiyang Yuan, Ning Zhang, Tiantian Liu, Dawei Xu
Format: Article
Language:English
Published: Wiley 2022-11-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/ctm2.1111