Thyroid carcinoma‐featured telomerase activation and telomere maintenance: Biology and translational/clinical significance
Abstract Background Telomerase is a ribonucleoprotein complex consisting of a catalytic component telomerase reverse transcriptase (TERT), internal RNA template and other co‐factors, and its essential function is to synthesize telomeric DNA, repetitive TTAGGG sequences at the termini of linear chrom...
Main Authors: | Xiaotian Yuan, Huiyang Yuan, Ning Zhang, Tiantian Liu, Dawei Xu |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-11-01
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Series: | Clinical and Translational Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1002/ctm2.1111 |
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