Structure-function relationships of the LRRC8 subunits and subdomains of the volume-regulated anion channel (VRAC)

Structure-function relationships of the LRRC8 subunits and subdomains of the volume-regulated anion channel (VRAC)

Volume Regulated Anion Channels (VRAC) are critical contributors to cell volume homeostasis and are expressed ubiquitously in all vertebrate cells. VRAC sense increases in cell volume, and act to return cells to baseline volume in a process known as regulatory volume decrease (RVD) through the efflu...

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Bibliographic Details
Main Authors: Manolia R. Ghouli, Todd A. Fiacco, Devin K. Binder
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
VRAC
LRRC8A
LRRC8
subdomains
structure
function
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2022.962714/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2022.962714/full

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