Increased inducible nitric oxide synthase expression in organs is associated with a higher severity of H5N1 influenza virus infection.

Increased inducible nitric oxide synthase expression in organs is associated with a higher severity of H5N1 influenza virus infection.

BACKGROUND: The mechanisms of disease severity caused by H5N1 influenza virus infection remain somewhat unclear. Studies have indicated that a high viral load and an associated hyper inflammatory immune response are influential during the onset of infection. This dysregulated inflammatory response w...

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Bibliographic Details
Main Authors: Simon Burggraaf, John Bingham, Jean Payne, Wayne G Kimpton, John W Lowenthal, Andrew G D Bean
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3023712?pdf=render

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http://europepmc.org/articles/PMC3023712?pdf=render

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