Specific CpG sites methylation is associated with hematotoxicity in low-dose benzene-exposed workers

Specific CpG sites methylation is associated with hematotoxicity in low-dose benzene-exposed workers

Benzene is a broadly used industrial chemicals which causes various hematologic abnormalities in human. Altered DNA methylation has been proposed as epigenetic biomarkers in health risk evaluation of benzene exposure, yet the role of methylation at specific CpG sites in predicting hematological effe...

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Bibliographic Details
Main Authors: Feier Wang, Lizhu Ye, Xinhang Jiang, Rui Zhang, Shen Chen, Liping Chen, Hongyao Yu, Xiaowen Zeng, Daochuan Li, Xiumei Xing, Yongmei Xiao, Wen Chen
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Environment International
Subjects:
Benzene
Methylation of TRIM36, MGMT and RASSF1a genes
Specific CpG sites
Epi-biomarkers
Integrative damage
Risk assessment
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412024002319

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http://www.sciencedirect.com/science/article/pii/S0160412024002319

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