Discovery of Natural Inhibitors of Cholinesterases from <i>Hydrangea</i>: In Vitro and In Silico Approaches

Alzheimer’s disease (AD) is a neurodegenerative disease conceptualized as a clinical-biological neurodegenerative construct where amyloid-beta pathophysiology is supposed to play a role. The loss of cognitive functions is mostly characterized by the rapid hydrolysis of acetylcholine by cholinesteras...

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Bibliographic Details
Main Authors: Jayeong Hwang, Kumju Youn, Gyutae Lim, Jinhyuk Lee, Dong Hyun Kim, Mira Jun
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/13/1/254