High-resolution mass spectrometry identifies delayed biomarkers for improved precision in acetaminophen/paracetamol human biomonitoring

High-resolution mass spectrometry identifies delayed biomarkers for improved precision in acetaminophen/paracetamol human biomonitoring

Paracetamol/acetaminophen (N-acetyl-p-aminophenol, APAP) is a top selling analgesic used in more than 600 prescription and non-prescription pharmaceuticals. To study efficiently some of the potential undesirable effects associated with increasing APAP consumption (e.g., developmental disorders, drug...

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Bibliographic Details
Main Authors: Eva Gorrochategui, Marc Le Vee, Habiba Selmi, Anne Gérard, Jade Chaker, Annette M. Krais, Christian Lindh, Olivier Fardel, Cécile Chevrier, Pierre Le Cann, Gary W. Miller, Robert Barouki, Bernard Jégou, Thomas Gicquel, David M. Kristensen, Arthur David
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Environment International
Subjects:
Human biomonitoring
High-resolution mass spectrometry
Acetaminophen/paracetamol
Exposomics
Thiomethyl metabolites
Chemical exposome
Online Access:http://www.sciencedirect.com/science/article/pii/S016041202300572X

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http://www.sciencedirect.com/science/article/pii/S016041202300572X

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