Mechanical Genomic Studies Reveal the Role of <sc>d</sc>-Alanine Metabolism in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content> Cell Stiffness

Mechanical Genomic Studies Reveal the Role of <sc>d</sc>-Alanine Metabolism in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content> Cell Stiffness

ABSTRACT The stiffness of bacteria prevents cells from bursting due to the large osmotic pressure across the cell wall. Many successful antibiotic chemotherapies target elements that alter mechanical properties of bacteria, and yet a global view of the biochemistry underlying the regulation of bacte...

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Bibliographic Details
Main Authors: Rishi R. Trivedi, John A. Crooks, George K. Auer, Joel Pendry, Ilona P. Foik, Albert Siryaporn, Nicholas L. Abbott, Zemer Gitai, Douglas B. Weibel
Format: Article
Language:English
Published: American Society for Microbiology 2018-11-01
Series:mBio
Subjects:
cell stiffness
DadA
mechanical genomics
Pseudomonas aeruginosa
cell wall
Online Access:https://journals.asm.org/doi/10.1128/mBio.01340-18

Internet

https://journals.asm.org/doi/10.1128/mBio.01340-18

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