TLR4 Expression by Liver Resident Cells Mediates the Development of Glucose Intolerance and Insulin Resistance in Experimental Periodontitis.

Results from epidemiological studies indicate a close association between periodontitis and type 2 diabetes mellitus. However, the mechanism linking periodontitis to glucose intolerance (GI) and insulin resistance (IR) is unknown. We therefore tested the hypothesis that periodontitis induces the dev...

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Bibliographic Details
Main Authors: Vladimir Ilievski, Yale Cho, Priya Katwala, Heriberto Rodriguez, Margaret Tulowiecka, David Kurian, Lara Leoni, John W Christman, Terry G Unterman, Keiko Watanabe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4552742?pdf=render