Targeting mutant p53 in cancer: the latest insights

Abstract This commentary wishes to highlight the latest discoveries in the mutant p53 field that have been discussed in the 8th p53 Mutant Workshop 2019, held in Lyon. TP53 mutant (mutp53) proteins are involved in the pathogenesis of most human cancers. Mutp53 proteins not only lose wild-typ53 funct...

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Bibliographic Details
Main Authors: Silvia Di Agostino, Giulia Fontemaggi, Sabrina Strano, Giovanni Blandino, Gabriella D’Orazi
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13046-019-1302-0