Cell atlas of trabecular meshwork in glaucomatous non-human primates and DEGs related to tissue contract based on single-cell transcriptomics

Summary: As the major channel of aqueous humor outflow, dysfunction of trabecular meshwork (TM) can lead to intraocular pressure elevating, which can trigger primary open-angle glaucoma (POAG). In this study, we use single-cell RNA sequencing (scRNA-seq) technique to build an atlas and further explo...

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Bibliographic Details
Main Authors: Xu Jia, Jian Wu, Xiaohong Chen, Simeng Hou, Yangyang Li, Ling Zhao, Yingting Zhu, Zhidong Li, Caibin Deng, Wenru Su, Yehong Zhuo
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223021016