Tumoricidal, Temozolomide- and Radiation-Sensitizing Effects of K<sub>Ca</sub>3.1 K<sup>+</sup> Channel Targeting In Vitro Are Dependent on Glioma Cell Line and Stem Cell Fraction

Tumoricidal, Temozolomide- and Radiation-Sensitizing Effects of K<sub>Ca</sub>3.1 K<sup>+</sup> Channel Targeting In Vitro Are Dependent on Glioma Cell Line and Stem Cell Fraction

Reportedly, the intermediate-conductance Ca<sup>2+</sup>-activated potassium channel K<sub>Ca</sub>3.1 contributes to the invasion of glioma cells into healthy brain tissue and resistance to temozolomide and ionizing radiation. Therefore, K<sub>Ca</sub>3.1 has bee...

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Bibliographic Details
Main Authors: Nicolai Stransky, Katrin Ganser, Ulrike Naumann, Stephan M. Huber, Peter Ruth
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
glioma stem cells
colony formation assay
limited dilution assay
TRAM-34
temozolomide
ionizing radiation
Online Access:https://www.mdpi.com/2072-6694/14/24/6199

Internet

https://www.mdpi.com/2072-6694/14/24/6199

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