Suppression of spermatogenesis by testosterone undecanoate-loaded injectable in situ-forming implants in adult male rats

Suppression of spermatogenesis by testosterone undecanoate-loaded injectable in situ-forming implants in adult male rats

We have investigated the feasibility of administration of testosterone undecanoate (TU)-loaded injectable in situ-forming implant (ISFI) for contraception in adult male Sprague-Dawley rats. Male rats were treated with vehicle, TU-loaded ISFIs (540, 270 and 135 mg TU kg−1 ) or TU injections (45 mg TU...

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Bibliographic Details
Main Authors: Xiao-Wei Zhang, Chong Zhang, Wei Zhang, Dan Yang, Shu Meng, Ping Wang, Jing Guo, Dan-Hua Liu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Asian Journal of Andrology
Subjects:
in situ -forming implants; male contraception; rats; spermatogenesis; testosterone undecanoate
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2016;volume=18;issue=5;spage=791;epage=797;aulast=Zhang

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http://www.ajandrology.com/article.asp?issn=1008-682X;year=2016;volume=18;issue=5;spage=791;epage=797;aulast=Zhang

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